PARTNER CONTENT
Enzyme, winner of the Blockchain Technology of the Year award at the Hedgeweek Global Digital Assets Awards 2025, provides a comprehensive infrastructure to allow clients to manage on-chain assets efficiently, optimize operational processes, and develop innovative financial strategies. Here, Founder Mona El Isa outlines what sets the company apart and how it is addressing current challenges and opportunities…
In no more than 50 words, please describe your firm’s service offering and what makes it special?
Enzyme is global infrastructure that enables businesses and institutions to create and manage tokenized products – helping them integrate decentralization into their financial systems. Enzyme’s Vault-as-a-Service and Financial Instruments product lines enable you to launch tokenized funds, structured products, term deposits, collateralized debt instruments, and more.
What product or service innovation from the past 12 months are you most proud of?
While we continue to develop Enzyme.Blue, our flagship digital asset management platform, we’re preparing to launch Enzyme.Onyx – with several industry leaders already testing the solution. Onyx introduces a groundbreaking approach to tokenized strategy creation: a modular vault tokenization layer designed for enterprises looking to build across any asset class, protocol, or financial system.
With Onyx, Enzyme Vaults can be deployed onto any wallet architecture—enabling secure, multi-party tokenized subscriptions and unlocking cross-chain capabilities, access to unlimited protocols, and support for both decentralized and centralized assets.
We’re also proud to highlight the momentum of Enzyme.Myso – a fully decentralized options protocol for creating and managing bespoke on-chain covered calls and cash-secured puts. In the past three months alone, Myso has surpassed $40M in notional volume and $1.5M in premium distributed, marking an 8x growth.
What has been the most significant change you’ve observed in the global crypto industry in the past 12 months?
The most significant shift over the past 12 months has been the acceleration of traditional finance moving on-chain. It’s no longer a question of if, but how fast adoption will unfold.
This shift has triggered a wave of adaptation across the crypto industry. We’ve seen a clear professionalization at all levels – from infrastructure to user experience to regulatory readiness. Crypto-native players are evolving their offerings and value propositions to meet the expectations of institutional clients and support large-scale adoption that’s no longer hypothetical, but imminent.
We’ve also seen substantial progress in core infrastructure:
- The rise of Ethereum Layer 2s to support broader, scalable use cases
- A boom in stablecoin rails and enterprise-grade payment infrastructure
- And increasingly, the development of natively tokenized financial instruments—not just tokenized funds, but structured products, term deposits, and more complex DeFi applications
The growing maturity of the space is also reflected in M&A activity. Consolidation signals that crypto companies are reaching a level of maturity that makes them attractive to larger players. This drives emulation, raises the bar across the industry, and ultimately benefits users through better competition, interoperability, and trust.
What economic forces – in Europe and/or globally – do you anticipate having the biggest impact on your business over the next 12 months?
The convergence of major institutions and TradFi actors toward decentralized systems is set to be the most impactful trend for our business in the next 12 months.
Alongside the well-understood stablecoin use case that’s transforming global payments, we’re now seeing serious traction on more complex, high-value applications. Traditional funds are being tokenized, yes—but more notably, we’re entering a phase where entities are tackling natively on-chain financial instruments: structured products, term deposits, collateralized strategies, truly native tokenized funds and more. These developments mark a shift from experimentation to real infrastructure being built around decentralized logic.
This is precisely what Enzyme was built for. Our infrastructure enables the creation and management of tokenized financial products—and is uniquely positioned to support this wave of convergence.
Which are the most significant challenges facing the industry currently and what role can technology play in helping private markets professionals – in the front and/or back office – manage them?
One of the most significant challenges facing the industry today is the fragmentation, inefficiency, and opacity of private markets infrastructure. Processes are still largely manual, data is siloed, and operations are weighed down by intermediaries – leading to high costs, slow settlement, and limited access to real-time information.
On the front office side, this limits flexibility and innovation in product design, investor onboarding, and secondary market liquidity. On the back office, it creates operational drag: from reconciliation and reporting to compliance and fund administration.
Technology – particularly tokenization and programmable infrastructure – can radically streamline these bottlenecks.
- Tokenized financial products reduce operational friction by embedding logic for settlement, compliance, and asset servicing directly into smart contracts.
- On-chain transparency and automation allow for real-time reporting, auditable flows, and reduced reliance on middlemen.
- Composable infrastructure enables private markets professionals to design, launch, and manage new financial instruments more efficiently—tailored to investor needs and regulatory constraints.
Ultimately, the role of technology is to remove unnecessary complexity, increase access, and make private markets as fluid and transparent as public ones – without compromising security or compliance.
Mona El Isa, Co-Founder, Enzyme – Mona, Co-founder of Enzyme and Founder/CEO of Avantgarde Finance, brings a wealth of experience from traditional finance to the forefront of decentralised innovation. A former Vice President at Goldman Sachs, she earned recognition as one of Trader Magazine’s “Top 30 under 30” in 2008 and Forbes’ “30 under 30” in 2011. After joining Geneva-based macro fund Jabre Capital in 2011, Mona’s vision shifted in 2014 when she identified blockchain as the future of finance. In 2017, she founded Enzyme, driven by the mission to level the investment playing field and empower the democratisation of decentralised finance with cutting-edge infrastructure.
